Bio-Collagen Real Deep Mask

Aqua (Water) — CIR Expert Panel Safety Assessment: The CIR Expert Panel concludes that water (aqua) is safe as used in cosmetic formulations.

CTPA Ingredient Library — Aqua (Water): Water is the most commonly used cosmetic ingredient and is listed as safe by the CTPA with no restrictions on use.

FDA GRAS Database — Glycerin: Glycerin (glycerol) is affirmed as Generally Recognized As Safe (GRAS) by the FDA. As a cosmetic ingredient, it is one of the most widely used and well-tolerated humectants, drawing moisture from the environment to the outer layers of the skin.

CIR Safety Assessment of Acrylates Copolymers as Used in Cosmetics (2012): The CIR Expert Panel concluded that acrylates copolymer is safe for use in cosmetics as a film former, binder, and rheology modifier at the concentrations used in current practice. The high molecular weight polymer is not absorbed through intact skin.

Niacinamide (Vitamin B3) — FDA Cosmetic Ingredient Review: Niacinamide is considered safe for use in cosmetics. It is a well-established skin-conditioning agent with evidence supporting its role in improving skin texture, tone, and barrier function.

CTPA Ingredient Library — Niacinamide: CTPA lists niacinamide as a safe and effective skin-conditioning agent widely used across cosmetic formulations, with a strong safety profile across concentrations typically used in cosmetics (2–10%).

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CIR Safety Assessment of Chondrus Crispus (Carrageenan) as Used in Cosmetics: The CIR Expert Panel concluded that Chondrus Crispus Extract (carrageenan) is safe for use in cosmetics as a thickening agent and skin-conditioning ingredient. The topically applied cosmetic-grade extract does not present the same concerns as orally ingested degraded carrageenan.

CIR Safety Assessment of Propylene Glycol and Related Ingredients as Used in Cosmetics: The CIR Expert Panel concluded that dipropylene glycol is safe for use in cosmetics as a solvent and humectant. It has low irritation and sensitisation potential at cosmetic use concentrations.

Betaine — CIR Expert Panel Safety Assessment: The CIR Expert Panel found betaine safe as used in cosmetics; it is well tolerated across all skin types with no significant adverse effects reported.

CTPA Ingredient Library — Betaine: CTPA recognises betaine as a well-established skin-conditioning agent and humectant with a strong safety profile, suitable for sensitive skin formulations.

CIR Safety Assessment of Algin and Alginic Acid as Used in Cosmetics: The CIR Expert Panel concluded that algin (alginic acid and its salts) is safe for use in cosmetics as a thickening agent and film former. It is derived from brown seaweed and has a long history of safe cosmetic use.

CIR Safety Assessment of Agar as Used in Cosmetics: The CIR Expert Panel concluded that agar is safe for use in cosmetics as a thickening agent and gelling ingredient. It is derived from red algae and has an extensive history of safe use in food and cosmetic applications.

CTPA Ingredient Library — Hydroxyacetophenone: CTPA recognises hydroxyacetophenone as a cosmetic ingredient used for its antioxidant and antimicrobial-enhancing properties. It functions as a skin-conditioning agent and preservative booster with a good safety profile at the concentrations used in cosmetic formulations.

CIR Safety Assessment of 1,2-Hexanediol as Used in Cosmetics: The CIR Expert Panel found 1,2-hexanediol safe as used in cosmetics. It functions as a humectant and antimicrobial preservative booster, enhancing the efficacy of other preservatives. No significant dermal irritation or sensitisation was identified at concentrations used in cosmetic formulations.

CTPA Ingredient Library — 1,2-Hexanediol: CTPA lists 1,2-hexanediol as a safe humectant and preservative booster used in cosmetics. It is considered non-irritating at concentrations typically found in leave-on and rinse-off formulations and is widely used as a paraben-free preservation system component.

CIR Safety Assessment of Potassium Chloride as Used in Cosmetics: The CIR Expert Panel concluded that potassium chloride is safe for use in cosmetics as a viscosity-adjusting agent. It is a naturally occurring salt with an extensive safety record in both food and cosmetic applications.

CIR Safety Assessment of Caprylyl Glycol: The CIR Expert Panel concludes that caprylyl glycol is safe as used in cosmetic formulations as a skin conditioner and preservative booster.

CTPA Cosmetic Ingredients — Caprylyl Glycol: Caprylyl glycol is approved for cosmetic use in the EU as a multifunctional ingredient providing skin conditioning and antimicrobial preservation boosting activity.

FDA — Sucrose as a Cosmetic Ingredient: The FDA permits sucrose (common sugar) for use in cosmetics. It functions as a humectant and skin-conditioning agent and has a long history of safe use in cosmetic formulations. No safety restrictions apply at concentrations used in cosmetics.

CTPA Ingredient Library — Sucrose: CTPA lists sucrose as a safe cosmetic ingredient used as a humectant and skin-conditioning agent. It is derived from sugar cane or sugar beet and is considered non-irritating and safe for all skin types at cosmetic concentrations.

FDA OTC Skin Protectant Active Ingredient — Allantoin: The FDA recognises allantoin as a safe and effective OTC skin protectant active ingredient at concentrations of 0.5–2.0%. It soothes and protects irritated skin and helps relieve minor skin irritation from chapping, chafing, and wind.

CTPA Ingredient Library — Allantoin: CTPA lists allantoin as a safe, soothing skin-conditioning agent with a long history of safe use as a skin protectant. It is well tolerated by sensitive and reactive skin types.

CTPA Ingredient Library — Polyglyceryl-10 Laurate: CTPA lists polyglyceryl esters including polyglyceryl-10 laurate as safe, biodegradable emulsifiers with a low sensitisation potential, widely used in rinse-off and leave-on products.

CIR Safety Assessment of Ethylhexylglycerin as Used in Cosmetics: The CIR Expert Panel found ethylhexylglycerin safe as used in cosmetics. It functions as a skin-conditioning agent and preservative booster enhancing the efficacy of other preservatives. No significant irritation or sensitisation was identified at cosmetic concentrations.

CTPA Ingredient Library — Ethylhexylglycerin: CTPA lists ethylhexylglycerin as a safe skin-conditioning agent and preservative enhancer. It is used in cosmetics to improve formula feel and boost preservation systems, and is considered non-irritating for most skin types.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

Korean MFDS — Approved Functional Cosmetic Ingredients for Wrinkles: Adenosine: Adenosine is listed as an approved functional cosmetic ingredient by the Korean Ministry of Food and Drug Safety (MFDS) for anti-wrinkle claims at 0.04% in finished products. Clinical data demonstrates reduction in fine lines and improvement in skin elasticity.

Disodium EDTA — CIR Expert Panel Safety Assessment: The CIR Expert Panel concluded that disodium EDTA is safe as used in cosmetic formulations. The concentrations typically used (0.01–0.1%) are well within safe limits.

CTPA Ingredient Library — Disodium EDTA: CTPA lists disodium EDTA as a safe chelating agent with a well-established safety record in cosmetics; it enhances preservative systems and formula stability.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CTPA Ingredient Library — Rosa Damascena Flower Water: CTPA recognises Rosa Damascena Flower Water (rose water) as a cosmetic ingredient derived from steam distillation of rose petals. It is used as a skin-conditioning agent and fragrance component with a long history of safe cosmetic use.

CIR Safety Assessment of Hydrolyzed Collagen as Used in Cosmetics: The CIR Expert Panel concluded that hydrolyzed collagen and related collagen-derived ingredients are safe for use in cosmetics as skin-conditioning agents. Topically applied collagen does not replace or supplement dermal collagen; it acts as a surface humectant and film former.

CTPA Ingredient Library — Iris Florentina Root Extract: CTPA notes that Iris Florentina Root Extract (orris root) contains fragrance-active irone compounds that are recognised as potential allergens in cosmetic formulations. Sensitive individuals or those with known fragrance allergies should be cautious with products containing this ingredient.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

Butylene Glycol — CIR Expert Panel Safety Assessment: The CIR Expert Panel concluded that butylene glycol is safe as used in cosmetic formulations; it is a well-tolerated humectant and solvent.

CTPA Ingredient Library — Butylene Glycol: CTPA classifies butylene glycol as a safe skin-conditioning humectant and solvent with a strong tolerability record across skin types including sensitive skin.

CIR Safety Assessment of Glycyrrhiza Glabra (Licorice) Derivatives as Used in Cosmetics: The CIR Expert Panel concluded that dipotassium glycyrrhizate and related licorice-derived ingredients are safe for use in cosmetics as skin-conditioning agents. These ingredients have a long history of use in cosmetics for their soothing and anti-inflammatory properties.

CIR Safety Assessment of Hyaluronic Acid and Its Salts as Used in Cosmetics (2020): The CIR Expert Panel concluded that hyaluronic acid and its derivatives including hydrolyzed hyaluronic acid are safe for use in cosmetics as skin-conditioning agents and humectants at the concentrations used in current practice.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CTPA — Tocopherol (Vitamin E) in Cosmetics: Tocopherol and its esters are widely used antioxidants in cosmetic formulations. The CTPA confirms that tocopherol has an excellent safety profile in cosmetic applications and provides meaningful protection against oxidative degradation of skin lipids.