Hyaluronic Acid 2% + B5 (with Ceramides)

CIR Safety Assessment of Water as Used in Cosmetics: Water (Aqua) is reviewed by the CIR Expert Panel and is widely accepted as safe for use in cosmetic products. It functions as a solvent and vehicle for delivering other ingredients to the skin.

FDA Briefing on Hyaluronic Acid in Topical Formulations: Sodium hyaluronate is generally recognized as safe (GRAS) as a cosmetic ingredient. It functions as an effective humectant and skin-conditioning agent suitable for all skin types.

CIR Safety Assessment of Propanediol as Used in Cosmetics (2015): The CIR Expert Panel concluded that propanediol is safe for use in cosmetic products. It functions as a humectant, solvent, and viscosity-controlling agent with a low sensitisation potential.

CTPA Ingredient Library — Pentylene Glycol: Pentylene Glycol is approved for use in cosmetics as a humectant and solvent. It is considered safe at concentrations used in leave-on and rinse-off formulations.

CIR Safety Assessment of Hyaluronic Acid and Its Salts as Used in Cosmetics (2020): The CIR Expert Panel concluded that hyaluronic acid and its derivatives including hydrolyzed hyaluronic acid are safe for use in cosmetics as skin-conditioning agents and humectants at the concentrations used in current practice.

CIR Safety Assessment of Sodium Hyaluronate Crosspolymer: The CIR Expert Panel has assessed Cross-Linked Hyaluronic Acid and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Forms moisture-retaining film on skin surface

CTPA Cosmetic Ingredient Profile — Sodium Hyaluronate Crosspolymer: The CTPA lists Cross-Linked Hyaluronic Acid as a safe and well-established cosmetic ingredient. Prolonged hydration effect

CIR Safety Assessment of Phospholipids: The CIR Expert Panel has assessed Phospholipids and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Mimic skin's natural lipid barrier

CTPA Cosmetic Ingredient Profile — Phospholipids: The CTPA lists Phospholipids as a safe and well-established cosmetic ingredient. Restore and strengthen the skin barrier

CIR Safety Assessment of Sphingolipids: The CIR Expert Panel has assessed Sphingolipids and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Naturally found in the skin barrier

CTPA Cosmetic Ingredient Profile — Sphingolipids: The CTPA lists Sphingolipids as a safe and well-established cosmetic ingredient. Maintain skin integrity and prevent moisture loss

CIR Safety Assessment of Panthenol as Used in Cosmetics: The CIR Expert Panel found panthenol (provitamin B5) safe as used in cosmetic formulations. It functions as a humectant and skin-conditioning agent, improving skin hydration and supporting barrier function, with no significant irritation or sensitisation concerns.

CTPA Ingredient Library — Panthenol: CTPA lists panthenol as a safe humectant and skin-conditioning agent. As provitamin B5, it supports healthy skin cell metabolism. It is well tolerated and considered safe for sensitive skin.

CIR Safety Assessment of Ahnfeltiopsis Concinna Extract: The CIR Expert Panel has assessed Red Algae Extract and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Rich in polysaccharides that hydrate and soothe skin

CTPA Cosmetic Ingredient Profile — Ahnfeltiopsis Concinna Extract: The CTPA lists Red Algae Extract as a safe and well-established cosmetic ingredient. Conditioning and smoothing effect

FDA GRAS Database — Glycerin: Glycerin (glycerol) is affirmed as Generally Recognized As Safe (GRAS) by the FDA. As a cosmetic ingredient, it is one of the most widely used and well-tolerated humectants, drawing moisture from the environment to the outer layers of the skin.

CIR Safety Assessment of Polysorbates as Used in Cosmetics (2016): The CIR Expert Panel concluded that polysorbate 20 is safe for use in cosmetic products as an emulsifier and solubiliser at the concentrations used in current practice.

CIR Safety Assessment of Alpha Hydroxy Acids as Used in Cosmetics: The CIR Expert Panel reviewed citric acid as part of its assessment of alpha hydroxy acids. It is safe at concentrations used as a pH adjuster. At higher active exfoliant concentrations, the Panel recommended consumer advisories on increased photosensitivity.

CTPA Ingredient Library — Citric Acid: CTPA lists citric acid as a safe, permitted cosmetic ingredient functioning as a pH adjuster. At higher concentrations where it acts as an active AHA exfoliant, CTPA advises appropriate labelling regarding potential skin sensitivity.

CIR Safety Assessment of Citric Acid and Sodium Citrate as Used in Cosmetics (2014): The CIR Expert Panel concluded that sodium citrate is safe for use in cosmetics as a buffering and chelating agent. Sodium citrate is the sodium salt of citric acid and is also FDA GRAS (Generally Recognised as Safe) for food use, reflecting its well-established safety profile.

CIR Safety Assessment of p-Anisic Acid: The CIR Expert Panel has assessed Para-Anisic Acid and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Natural preservative derived from anise

CTPA Cosmetic Ingredient Profile — p-Anisic Acid: The CTPA lists Para-Anisic Acid as a safe and well-established cosmetic ingredient. Gentler alternative to traditional preservatives

CTPA — Tocopherol (Vitamin E) in Cosmetics: Tocopherol and its esters are widely used antioxidants in cosmetic formulations. The CTPA confirms that tocopherol has an excellent safety profile in cosmetic applications and provides meaningful protection against oxidative degradation of skin lipids.

CIR/FDA Ingredient Assessment — Not Found in Regulatory Databases: No published safety assessment was found for this ingredient in the CIR (Cosmetic Ingredient Review), FDA, CTPA, or MFDS regulatory databases at the time of review. This does not necessarily indicate a safety concern; many ingredients in common use have not been formally assessed by these bodies.

CIR Safety Assessment of Caprylyl Glycol: The CIR Expert Panel concludes that caprylyl glycol is safe as used in cosmetic formulations as a skin conditioner and preservative booster.

CTPA Cosmetic Ingredients — Caprylyl Glycol: Caprylyl glycol is approved for cosmetic use in the EU as a multifunctional ingredient providing skin conditioning and antimicrobial preservation boosting activity.

CTPA Ingredient Library — Ethoxydiglycol: Ethoxydiglycol is listed as a safe solvent in cosmetic formulations by CTPA. It is used to improve product texture and ingredient delivery.

CIR Safety Assessment of Ethylhexylglycerin as Used in Cosmetics: The CIR Expert Panel found ethylhexylglycerin safe as used in cosmetics. It functions as a skin-conditioning agent and preservative booster enhancing the efficacy of other preservatives. No significant irritation or sensitisation was identified at cosmetic concentrations.

CTPA Ingredient Library — Ethylhexylglycerin: CTPA lists ethylhexylglycerin as a safe skin-conditioning agent and preservative enhancer. It is used in cosmetics to improve formula feel and boost preservation systems, and is considered non-irritating for most skin types.

CIR Safety Assessment of Hexylene Glycol: The CIR Expert Panel concludes that hexylene glycol is safe as used in cosmetics at concentrations up to 1.6%; higher concentrations may cause irritation.

CTPA Cosmetic Ingredients — Hexylene Glycol: Hexylene glycol is listed as a potential skin sensitiser under EU Cosmetics Regulation when used at elevated concentrations. It is restricted to use as a solvent and preservative booster at low levels in finished products.

FDA — Phenoxyethanol in Cosmetics: FDA has reviewed phenoxyethanol as a cosmetic preservative and considers it safe at concentrations up to 1.0% in cosmetic products. FDA advises caution in products used around the mouth of infants.

CTPA Ingredient Library — Phenoxyethanol: CTPA confirms phenoxyethanol is a permitted cosmetic preservative under EU Cosmetics Regulation at a maximum concentration of 1.0%, and is considered safe for use in both rinse-off and leave-on products.

CTPA Ingredient Library — Chlorphenesin: Chlorphenesin is a permitted cosmetic preservative under EU Cosmetics Regulation (max 0.3% in rinse-off, max 0.2% in leave-on products). CTPA considers it safe when used within these limits.