Vanicream Daily Facial Moisturizer

CIR Safety Assessment of Purified Water: The CIR Expert Panel has assessed Water and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Primary solvent that dissolves and delivers active ingredients

CTPA Cosmetic Ingredient Profile — Purified Water: The CTPA lists Water as a safe and well-established cosmetic ingredient. Primary solvent that dissolves and delivers active ingredients

CIR Safety Assessment of Squalane as Used in Cosmetics: The CIR Expert Panel found squalane safe as used in cosmetics. It is a saturated hydrocarbon emollient that closely resembles squalene produced naturally by human sebaceous glands. It is well tolerated and non-irritating.

CTPA Ingredient Library — Squalane: CTPA lists squalane as a safe emollient and skin-conditioning agent. It is a skin-identical lipid that provides moisturisation without greasiness and is considered non-comedogenic and well tolerated by all skin types.

FDA GRAS Database — Glycerin: Glycerin (glycerol) is affirmed as Generally Recognized As Safe (GRAS) by the FDA. As a cosmetic ingredient, it is one of the most widely used and well-tolerated humectants, drawing moisture from the environment to the outer layers of the skin.

CTPA Ingredient Library — Pentylene Glycol: Pentylene Glycol is approved for use in cosmetics as a humectant and solvent. It is considered safe at concentrations used in leave-on and rinse-off formulations.

CIR Safety Assessment of Polyglyceryl-2 Stearate: The CIR Expert Panel has assessed Plant-Derived Emulsifier and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Mild plant-derived emulsifier blending oil and water

CTPA Cosmetic Ingredient Profile — Polyglyceryl-2 Stearate: The CTPA lists Plant-Derived Emulsifier as a safe and well-established cosmetic ingredient. Well-suited for sensitive skin formulas

CIR Safety Assessment of Glyceryl Stearate as Used in Cosmetics: The CIR Expert Panel concluded that glyceryl stearate is safe for use in cosmetics as an emollient and emulsifier at the concentrations used in current practice.

CIR Safety Assessment of Stearyl Alcohol: The CIR Expert Panel has assessed Fatty Alcohol and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Conditions skin

CTPA Cosmetic Ingredient Profile — Stearyl Alcohol: The CTPA lists Fatty Alcohol as a safe and well-established cosmetic ingredient. Thickens formulas

CIR Safety Assessment of Hyaluronic Acid: The CIR Expert Panel has assessed Hyaluronic Acid and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Holds up to 1000x its weight in water

CTPA Cosmetic Ingredient Profile — Hyaluronic Acid: The CTPA lists Hyaluronic Acid as a safe and well-established cosmetic ingredient. Provides intense hydration and plumping effect

CIR Safety Assessment of Ceramide EOP: The CIR Expert Panel has assessed Ceramide EOP and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Naturally found in the skin barrier

CTPA Cosmetic Ingredient Profile — Ceramide EOP: The CTPA lists Ceramide EOP as a safe and well-established cosmetic ingredient. Restores lipid barrier integrity

CIR Safety Assessment of Ceramide NG: The CIR Expert Panel has assessed Ceramide NG and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Replenishes skin's lipid barrier

CTPA Cosmetic Ingredient Profile — Ceramide NG: The CTPA lists Ceramide NG as a safe and well-established cosmetic ingredient. Improves moisture retention

CTPA Skin Barrier Science — Ceramides in Cosmetic Formulations: Ceramides are endogenous lipids critical to the skin barrier. Topical application of ceramide NP (ceramide 3) has been shown in peer-reviewed studies to restore stratum corneum lipid composition, reduce transepidermal water loss, and improve symptoms of atopic dermatitis.

CIR Safety Assessment of Ceramide AS: The CIR Expert Panel has assessed Ceramide AS and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Reinforces skin's natural barrier

CTPA Cosmetic Ingredient Profile — Ceramide AS: The CTPA lists Ceramide AS as a safe and well-established cosmetic ingredient. Reduces moisture loss

CIR Safety Assessment of Ceramide AP: The CIR Expert Panel has assessed Ceramide AP (Phytoceramide) and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Supports skin barrier by replenishing essential lipids

CTPA Cosmetic Ingredient Profile — Ceramide AP: The CTPA lists Ceramide AP (Phytoceramide) as a safe and well-established cosmetic ingredient. Reduces transepidermal water loss

CTPA Cosmetic Ingredient Profile — Carnosine: The CTPA lists Carnosine (Dipeptide) as a safe and well-established cosmetic ingredient. Helps protect against glycation (skin aging)

CIR Safety Assessment of Carnosine: The CIR Expert Panel has assessed Carnosine (Dipeptide) and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Antioxidant protecting skin cells from oxidative stress

CIR Safety Assessment of Hydrogenated Lecithin: The CIR Expert Panel has assessed Hydrogenated Lecithin and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Emollient that conditions skin

CTPA Cosmetic Ingredient Profile — Hydrogenated Lecithin: The CTPA lists Hydrogenated Lecithin as a safe and well-established cosmetic ingredient. Reinforces the skin's natural lipid barrier

CIR Safety Assessment of Phytosterols as Used in Cosmetics: The CIR Expert Panel found phytosterols safe as used in cosmetics. They function as skin-conditioning agents that help support skin barrier function, and are structurally similar to cholesterol — a natural component of the skin barrier. No significant irritation or sensitisation was identified.

CTPA Ingredient Library — Phytosterols: CTPA lists phytosterols as safe skin-conditioning agents derived from plant sources. They are used in cosmetics for their barrier-supporting properties and are considered safe and non-sensitising at concentrations used in cosmetic formulations.

CIR Safety Assessment of Caprylyl Glycol: The CIR Expert Panel concludes that caprylyl glycol is safe as used in cosmetic formulations as a skin conditioner and preservative booster.

CTPA Cosmetic Ingredients — Caprylyl Glycol: Caprylyl glycol is approved for cosmetic use in the EU as a multifunctional ingredient providing skin conditioning and antimicrobial preservation boosting activity.

CIR Safety Assessment of Polyacrylate Crosspolymer-11: The CIR Expert Panel has assessed Synthetic Polymer Thickener and concluded it is safe as used in cosmetic formulations. Primary documented benefit: Thickens and stabilizes emulsions

CTPA Cosmetic Ingredient Profile — Polyacrylate Crosspolymer-11: The CTPA lists Synthetic Polymer Thickener as a safe and well-established cosmetic ingredient. Provides smooth elegant texture

CIR Safety Assessment of 1,2-Hexanediol as Used in Cosmetics: The CIR Expert Panel found 1,2-hexanediol safe as used in cosmetics. It functions as a humectant and antimicrobial preservative booster, enhancing the efficacy of other preservatives. No significant dermal irritation or sensitisation was identified at concentrations used in cosmetic formulations.

CTPA Ingredient Library — 1,2-Hexanediol: CTPA lists 1,2-hexanediol as a safe humectant and preservative booster used in cosmetics. It is considered non-irritating at concentrations typically found in leave-on and rinse-off formulations and is widely used as a paraben-free preservation system component.